Agnostiq

Agnostiq is a Toronto-based quantum computing SaaS company founded in 2018 that has developed Covalent, an open-source workflow orchestration platform that democratizes access to quantum and high-performance computing resources, enabling researchers and developers to seamlessly orchestrate experiments across heterogeneous computing environments including quantum processors, CPUs, GPUs, and cloud resources through intelligent task scheduling and modular Python components, with $2 million in funding and evolution to commercial Covalent Cloud platform for AI infrastructure management.

Algorithmiq

Algorithmiq develops quantum algorithms and software for drug discovery and pharmaceutical research, focusing on quantum-enhanced molecular simulation and optimization techniques to accelerate the development of new medicines by solving complex computational problems in chemistry and biology that are intractable for classical computers. In February 2025, Algorithmiq partnered with Quantum Circuits to leverage the Aqumen Seeker full-stack quantum computing system featuring industry-first dual-rail qubits with built-in error detection for more accurate chemistry calculations and enzyme pharmacokinetics modeling. The company has raised $15 million in Series A funding (2023) following a $4 million seed round, with backing from Tiger Global and the European Investment Bank. Algorithmiq’s multiscale approach combines quantum computing and AI to revolutionize drug discovery, with recent publications on quantum algorithms for BODIPY molecules in photodynamic therapy applications and collaborations with IBM on quantum computer fine-tuning for pharmaceutical applications.

ApexQubit

ApexQubit is a US quantum software company founded in 2021 that develops quantum computing software platforms and tools for quantum algorithm development, quantum circuit optimization, and quantum application deployment, providing software solutions that enable researchers and enterprises to harness quantum computing capabilities for solving complex computational problems across various industries including finance, optimization, and scientific computing, with focus on making quantum computing more accessible through user-friendly software interfaces.

Company Information

• Founded: 2021
• Country: United States
• Website: https://apexqubit.com
• Categories: software

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BlueQubit

BlueQubit is a US quantum software company founded in 2022 that develops quantum algorithms and software platforms for quantum computing applications, focusing on creating accessible quantum development tools and algorithm implementations that enable researchers and developers to build and deploy quantum applications across various quantum hardware platforms, providing software solutions for optimization, machine learning, and simulation problems that can benefit from quantum computing approaches.

Company Information

• Founded: 2022
• Country: United States
• Website: https://bluequbit.io
• Categories: software

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Entropica Labs

Entropica Labs specializes in quantum machine learning algorithms and software tools that leverage quantum computing to enhance machine learning capabilities, developing quantum neural networks, quantum optimization algorithms, and hybrid quantum-classical approaches for applications in finance, healthcare, and artificial intelligence.

Company Information

• Founded: 2018
• Country: Singapore
• Website: https://entropicalabs.com
• Categories: software

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Horizon Quantum Computing

Horizon Quantum Computing creates quantum software development tools and compilers that automatically translate conventional programming languages into quantum circuits, making quantum computing accessible to classical software developers without requiring deep quantum expertise while optimizing quantum programs for different hardware platforms and applications. In September 2025, Horizon Quantum announced a merger with dMY Squared Technology Group in a SPAC transaction valued at approximately $503 million, with Horizon Quantum’s Class A ordinary shares expected to be listed on Nasdaq under the ticker HQ once the deal closes in projected Q1 2026. The merger will provide Horizon Quantum with significant capital to accelerate product development and global expansion of its quantum software platform.

JoS Quantum

JoS QUANTUM is a Frankfurt-based quantum computing company founded in 2018 by Markus Braun and Niklas Hegemann that develops cutting-edge quantum optimization algorithms for quantitative finance, insurance, and energy markets, providing cloud-accessible GRUNDZUSTAND calculation engine that integrates various quantum and classical hardware for risk management, portfolio optimization, trading strategies, and fraud detection, serving clients including Deutsche Börse Group and DZ Bank while participating in German government-funded quantum research projects.

Kipu Quantum

Kipu Quantum is a German quantum software company founded in 2019 and based in Karlsruhe and Berlin that develops application- and hardware-specific quantum algorithms using digital compression methods to enable quantum advantage on today’s quantum processors, offering solutions including the first commercial quantum machine learning service with proven quantum advantage, HUBO optimization algorithms, and counterdiabatic protocols for clients including BASF logistics optimization and battery materials research, with €10.5 million in funding and strategic acquisition of PLANQK platform to serve over 250 organizations.

Nanoacademic

Nanoacademic Technologies is a Montreal-based quantum simulation software company founded in 2008 that develops atomistic and quantum modeling tools including QTCAD (the world’s first commercial finite-element modeling software for spin qubits), NanoDCAL for quantum transport, and RESCU for nanophysics simulation, enabling researchers to predict properties of next-generation materials and quantum devices before manufacturing, serving academic, government, and corporate quantum researchers with 13+ years of in-house developed algorithms and consultancy services for advanced modeling support.

ParityQC

ParityQC is the world’s only quantum architecture company founded in 2020 as a University of Innsbruck spinoff by Wolfgang Lechner and Magdalena Hauser, developing blueprints and ParityOS operating system for highly scalable quantum computers using parity quantum optimization, featuring a compiler that translates optimization problems to quantum algorithms with tailored hardware designs, with their architecture implemented in NEC’s first quantum processor and collaborations with DLR Quantum Computing Initiative to advance scalable, error-corrected quantum computing for industry applications.

Phaseshift Technologies

Phaseshift Technologies is a Canadian quantum software company founded in 2020 that develops comprehensive quantum software solutions including quantum development frameworks, simulation tools, and quantum algorithm implementations, providing software platforms that enable organizations to explore quantum computing applications and develop quantum algorithms for optimization, machine learning, and scientific computing problems, bridging the gap between quantum theory and practical quantum computing applications for enterprises and researchers.

Company Information

• Founded: 2020
• Country: Canada
• Website: https://phaseshift.com
• Categories: software

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qAIntum.ai

qAIntum.ai develops quantum neural networks and quantum artificial intelligence algorithms that leverage quantum computing principles to enhance machine learning capabilities, focusing on quantum-enhanced AI models for pattern recognition, optimization, and data analysis applications that could provide advantages over classical AI approaches.

Company Information

• Founded: 2021
• Country: United States
• Website: https://qaintum.ai
• Categories: software

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qBraid

qBraid is a US quantum computing platform company founded in 2021 that provides the world’s most connected cloud-based quantum development environment, offering unified access to 24+ quantum devices from Amazon Braket, Azure Quantum, and other providers through a single interface, supporting 18+ quantum SDKs with cross-framework conversion capabilities and qBraid Lab IDE, serving over 18,000 quantum developers with no-setup-required access to quantum hardware, simulators, and development tools for research and enterprise quantum applications.

Qiskit

Qiskit is IBM’s open-source quantum computing framework launched in 2017 that has become the world’s most widely used quantum development platform, providing comprehensive tools for quantum circuit design, quantum algorithm implementation, quantum machine learning, and quantum application development, supporting quantum hardware from multiple providers and enabling researchers, developers, and students worldwide to learn quantum computing, build quantum applications, and contribute to the global quantum computing ecosystem through its extensive documentation, tutorials, and community support.

QPerfect

QPerfect provides a comprehensive quantum simulation platform that enables researchers and developers to model, simulate, and optimize quantum systems and algorithms using classical high-performance computing resources, offering tools for quantum circuit simulation, noise modeling, and quantum algorithm development to bridge the gap between quantum theory and practical implementation.

Company Information

• Founded: 2022
• Country: France
• Website: https://qperfect.io
• Categories: software

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Qruise

Qruise is a German quantum control software company founded in 2018 as a Forschungszentrum Jülich spinoff that develops machine learning-powered software for quantum device development, creating ‘digital twin’ simulators and automated optimization algorithms that replace manual work traditionally done by quantum physicists, with strategic partnerships with Quantum Machines and Zurich Instruments to integrate their ML Physicist software into quantum control systems for automated qubit tune-up, gate optimization, and device characterization across superconducting and Rydberg atom quantum platforms.

Qu&Co

Qu&Co was a Dutch quantum software company founded in 2017 that specialized in quantum computational chemistry and molecular simulation applications, developing quantum algorithms and software tools for drug discovery, materials science, and chemical modeling before being acquired and merged with Pasqal to enhance their neutral atom quantum computing platform with advanced quantum software capabilities, contributing their expertise in quantum chemistry algorithms to accelerate practical quantum applications in molecular simulation and materials research.

Quantagonia

In 2024-2025, quantum computing firm Quantagonia secured €4.3 million in seed funding led by Tensor Ventures to boost hybrid quantum computing and revolutionize AI solutions. Quantagonia’s Hybrid Quantum Platform aims to facilitate execution of existing program code on both classical and quantum computer architectures, paving the way for innovative AI-based solutions. The platform provides customers access to AI, optimization, and simulation applications, integrating seamlessly with leading manufacturers of classical hardware (CPUs & GPUs) and quantum hardware, enabling organizations to leverage quantum computing advantages while maintaining compatibility with existing infrastructure.

Quantastica

Quantastica is a Finnish quantum computing company founded in 2018 that provides quantum computing as a service through cloud-based platforms, offering quantum development tools, quantum simulators, and access to quantum hardware for researchers and enterprises, focusing on making quantum computing accessible through user-friendly interfaces and quantum algorithm development environments that enable organizations to experiment with quantum computing applications without requiring deep quantum expertise or hardware investments.

Company Information

• Founded: 2018
• Country: Finland
• Website: https://quantastica.com
• Categories: software

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Quantum Benchmark

Quantum Benchmark was a Canadian quantum software company founded in 2017 that specialized in quantum error diagnostics and quantum performance validation tools, developing True-Q software for quantum error characterization, gate set tomography, and quantum processor benchmarking that enabled quantum computing companies to optimize their systems and validate quantum operations, providing essential tools for quantum hardware development and quality control before being acquired by Keysight Technologies to enhance their quantum test and measurement portfolio, bringing advanced quantum error diagnostics capabilities to Keysight’s comprehensive quantum computing test solutions.

Quantum Computing Inc

Quantum Computing Inc (QCI) is a quantum software and applications company that secured $750 million in funding in October 2025, representing one of the largest quantum software investments in history. Founded in 2013, QCI develops quantum software platforms and applications enabling organizations to solve complex optimization problems using quantum and quantum-inspired algorithms. The company provides accessible quantum computing solutions for businesses without requiring deep quantum expertise through their ready-to-use quantum applications, Qatalyst quantum software platform, and consulting services. QCI’s technology portfolio includes quantum optimization solutions for logistics, supply chain management, financial modeling, and drug discovery applications. The company’s $750M funding round positions QCI as a major player in commercializing quantum software applications, with the capital supporting expansion of their enterprise quantum software offerings and acceleration of quantum-inspired algorithm development for near-term practical applications across multiple industries.

QunaSys

QunaSys is a Japanese quantum software company founded in 2018 that specializes in quantum chemistry software and molecular simulation applications, developing quantum algorithms and computational tools for chemical and pharmaceutical research, materials science, and drug discovery, providing software platforms that leverage quantum computing to solve complex molecular and chemical problems that are challenging for classical computers, serving research institutions and companies in Japan and globally seeking quantum advantages in chemical simulation and materials research.

Rahko

Rahko applies quantum machine learning algorithms to drug discovery and pharmaceutical research, developing quantum-enhanced computational methods for molecular analysis, drug-target interactions, and compound optimization that leverage quantum computing’s potential advantages in exploring complex chemical space for therapeutic applications.

Company Information

• Founded: 2018
• Country: United Kingdom
• Website: https://rahko.ai
• Categories: software

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Super.tech

Super.tech (acquired by Infleqtion) developed quantum-classical hybrid software solutions that integrate quantum computing capabilities with classical high-performance computing systems, creating unified platforms for solving optimization and simulation problems that benefit from both quantum and classical computational approaches.

Company Information

• Founded: 2021
• Country: Finland
• Website: https://super.tech
• Categories: software

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